How to Respond to an Opioid Overdose: Emergency Guide

August 13, 2025

man responding to an opioid overdose

If you’re wondering how to respond to an opioid overdose, knowing the signs and acting quickly can save a life.

Opioid overdose continues to be a major public health issue in Massachusetts and across the U.S. Whether you are in recovery, support someone who is, or are simply part of a community impacted by opioid use, understanding how to respond in an emergency is essential.

This guide outlines the life-saving steps to take during an overdose—no medical training required. Your quick action could make all the difference.

Recognizing the Signs of an Opioid Overdose

Overdoses can happen quickly and often silently. Learning to recognize the symptoms may help you act fast in a critical moment.

Common signs of an opioid overdose include:

  • Slow, shallow, or stopped breathing
  • Unresponsiveness or inability to wake up
  • Blue or gray lips, skin, or fingertips
  • Gurgling, snoring, or choking sounds
  • Very small (pinpoint) pupils

Even if you’re unsure, it’s always better to treat the situation as an overdose. Acting fast saves lives.

What to Do During an Opioid Overdose

1. Call 911 Immediately

Tell the dispatcher the person may be experiencing an overdose and share your exact location. Stay on the line and follow their instructions.

2. Check Responsiveness

Try to wake the person by calling their name and gently shaking them. If there is no response, try a sternum rub (firmly rub your knuckles on the center of their chest).

3. Administer Naloxone (Narcan)

If you have naloxone, use it right away. Follow the package instructions:

  • Spray naloxone into one nostril while the person is lying on their back.
  • If symptoms persist after 2–3 minutes, administer a second dose in the other nostril.

Naloxone temporarily blocks the effects of opioids, but professional medical care is still required.

4. Provide Rescue Breathing or CPR (If Trained)

If the person is not breathing, begin rescue breaths or CPR if you’re trained. If not, the 911 operator can guide you.

5. Stay with the Person

Stay until emergency services arrive. Turn them on their side (recovery position) to help prevent choking.

Where to Get Naloxone in Massachusetts

Naloxone is available without a prescription at most pharmacies in Massachusetts, including CVS, Walgreens, and local independent pharmacies.

You can also access free or low-cost naloxone through:

Many community organizations also offer naloxone training and kits. Carrying it could save a life.

Am I Protected by Massachusetts Law?

Yes. The Massachusetts Good Samaritan Law offers legal protection to anyone who seeks emergency help or administers naloxone during an overdose situation.

This means that if you call 911 or provide assistance, you will not be arrested or prosecuted for drug possession.

Frequently Asked Questions

What are the signs of an opioid overdose?

Look for slowed or stopped breathing, blue lips or skin, and unresponsiveness. Small pupils and gurgling sounds are also common.

Is naloxone safe to use?

Yes. Naloxone has no potential for misuse and will not harm someone even if they are not experiencing an opioid overdose.

Can I carry naloxone even if I’m not in healthcare?

Absolutely. Naloxone is available to anyone in Massachusetts and is often distributed through harm reduction programs and pharmacies.

What if I’m not sure whether it’s an overdose?

Always treat it like one. Administer naloxone and call for help. Acting quickly could save their life.

Find Help Near You in Massachusetts

If you or someone you care about is at risk of opioid overdose, Middlesex Recovery is here to help. We provide compassionate, evidence-based outpatient treatment for opioid and alcohol use disorders.

We have multiple clinic locations throughout Massachusetts, including:

  • Chelmsford, MA
  • Gloucester, MA
  • Norton, MA
  • Stoughton, MA
  • Woburn, MA

Each of our clinics offers medication-assisted treatment (MAT) options, including Suboxone® and Vivitrol®, alongside supportive counseling and recovery services.

Find a clinic near you:
View all Middlesex Recovery locations

Contact Middlesex Recovery Today

If opioid addiction is impacting your life or the life of someone you care about, reach out to our treatment center. We are here to provide the support and care you need to take the first step toward recovery.

Call 781.303.9936